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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLNS1A
All Species:
25.76
Human Site:
T207
Identified Species:
40.48
UniProt:
P54105
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54105
NP_001284.1
237
26215
T207
Y
N
M
A
G
V
R
T
E
D
S
I
R
D
Y
Chimpanzee
Pan troglodytes
XP_001175048
222
24569
S197
G
M
L
S
Q
S
V
S
S
Q
Y
N
M
A
G
Rhesus Macaque
Macaca mulatta
XP_001088333
203
22330
R178
V
R
T
E
D
S
I
R
D
Y
E
D
G
M
E
Dog
Lupus familis
XP_535567
226
24585
R201
V
R
T
E
D
S
I
R
D
Y
E
D
G
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61189
236
26003
T206
Y
N
M
A
G
V
R
T
E
D
S
V
R
N
Y
Rat
Rattus norvegicus
Q04753
236
26074
T206
Y
N
M
A
G
V
R
T
E
D
S
V
R
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519221
278
30242
T217
Y
H
M
A
G
V
R
T
D
D
S
S
R
D
F
Chicken
Gallus gallus
XP_423253
238
26615
T208
Y
N
M
A
G
V
R
T
E
D
S
I
R
E
F
Frog
Xenopus laevis
P54106
241
26428
T211
H
T
M
A
G
V
R
T
E
G
P
A
L
E
P
Zebra Danio
Brachydanio rerio
NP_571499
249
27316
T220
Y
H
M
A
G
V
R
T
E
E
P
D
A
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611237
215
23724
A190
E
A
M
E
E
D
D
A
L
T
L
G
R
N
G
Honey Bee
Apis mellifera
XP_624081
207
23224
T182
L
P
T
E
Q
I
G
T
N
H
N
G
T
E
A
Nematode Worm
Caenorhab. elegans
NP_001021287
205
22895
G180
H
M
Q
M
S
E
E
G
L
A
N
M
Q
R
I
Sea Urchin
Strong. purpuratus
XP_001194575
165
18108
L140
D
P
E
I
G
I
E
L
I
V
A
D
G
G
N
Poplar Tree
Populus trichocarpa
XP_002318279
231
25740
L206
H
D
L
A
R
T
V
L
E
L
Q
I
N
D
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
85.6
82.2
N.A.
90.3
90.3
N.A.
40.6
82.3
72.1
68.2
N.A.
20.2
40
29.9
24.4
Protein Similarity:
100
93.2
85.6
85.2
N.A.
94.9
94.9
N.A.
53.2
90.3
82.5
80.3
N.A.
37.5
56.5
45.5
40.9
P-Site Identity:
100
0
0
0
N.A.
86.6
86.6
N.A.
73.3
86.6
46.6
53.3
N.A.
13.3
6.6
0
6.6
P-Site Similarity:
100
20
6.6
6.6
N.A.
100
93.3
N.A.
93.3
100
60
73.3
N.A.
20
26.6
26.6
20
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
54
0
0
0
7
0
7
7
7
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
14
7
7
0
20
34
0
27
0
20
0
% D
% Glu:
7
0
7
27
7
7
14
0
47
7
14
0
0
20
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% F
% Gly:
7
0
0
0
54
0
7
7
0
7
0
14
20
7
14
% G
% His:
20
14
0
0
0
0
0
0
0
7
0
0
0
0
7
% H
% Ile:
0
0
0
7
0
14
14
0
7
0
0
20
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
14
0
0
0
0
14
14
7
7
0
7
0
0
% L
% Met:
0
14
54
7
0
0
0
0
0
0
0
7
7
14
0
% M
% Asn:
0
27
0
0
0
0
0
0
7
0
14
7
7
14
7
% N
% Pro:
0
14
0
0
0
0
0
0
0
0
14
0
0
0
7
% P
% Gln:
0
0
7
0
14
0
0
0
0
7
7
0
7
7
0
% Q
% Arg:
0
14
0
0
7
0
47
14
0
0
0
0
40
7
0
% R
% Ser:
0
0
0
7
7
20
0
7
7
0
34
7
0
0
0
% S
% Thr:
0
7
20
0
0
7
0
54
0
7
0
0
7
7
0
% T
% Val:
14
0
0
0
0
47
14
0
0
7
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
40
0
0
0
0
0
0
0
0
14
7
0
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _